Cedars Cardiac Suite combines several interactive stand-alone applications for the automatic segmentation, quantification and analysis of nuclear cardiology studies.

Quantitative Gated SPECT (QGS)

QGS is an interactive application for the automatic segmentation, quantification and analysis of static and gated short axis myocardial perfusion SPECT.

• Automatic generation of left ventricle (LV) inner and outer surfaces and valve plane from three- or four-dimensional (respectively static or gated) LV short axis perfusion SPECT data
• Display of stress and rest projection (raw) images in static and cine mode
• Computation of functional metrics
• Automatic generation of surfaces and polar maps
• Variety of modes for image data viewing from selected slices in a 2D view to rendered 3D surface of the myocardium with function maps
• Determination and display of the severity and extent of motion and thickening abnormalities using normal limits
• Automatic generation of the segmental motion and thickening scores based on a multi-segment, multiple-point scale

Quantitative Perfusion SPECT (QPS)

QPS is an interactive application for the automatic segmentation, quantification, analysis and display of static (ungated) short axis myocardial perfusion SPECT images.

• Automatic generation of left ventricle (LV) inner and outer surfaces and valve plan from LV short axis perfusion SPECT data
• Display of stress and rest projection (raw) images in static and cine mode
• Automatic computation of functional metrics including LV chamber volume and mid-myocardial surface area
• Automatic generation of stress, rest and reversibility surfaces and polar maps
• Determination and display of the severity and extent of perfusion defects using isotope- and gender-specific normal limits
• Automatic computation of global quantitative defect size, both in absolute terms and as a percentage of the mid-myocardial surface area
• Automatic generation of segmental perfusion scores

Quantitative Blood Pool SPECT (QBS)

QBS is an interactive application for the automatic segmentation and quantification of gated short axis blood pool (red blood cells, RBC), SPECT.

• Automatic generation of left- and right-ventricular endocardial surfaces and valve planes from three-dimensional (3D) gated short axis blood pool images
• Automatic calculation of left- and right-ventricular volumes and ejection fractions
• Two-dimensional (2D) image display using standard American College of Cardiology (ACC) cardiac SPECT conventions
• Display of projection (raw) images in static and cine mode
• Calculation of phase histograms from all gated images, including separate left-ventricular (LV) and right-ventricular (RV) histograms, ROIs for gated short axis SPECT images
• Computation of diastolic function metrics for the left and right ventricles
• Calculation and display of polar maps representing wall motion, including FFH amplitude and phase

Quantitative PET (QPET)

QPET is an interactive application for the automatic segmentation, quantification and analysis of static and gated myocardial perfusion PET, with support for both short axis and transverse datasets.

• PET Perfusion Databases allows normal-limit based quantification of Rb-82 and N-13-ammonia perfusion PET images using databases created from scans of low-likelihood patients
• Viability Quantification performs the quantitative assessment of “hibernating myocardium”
• Automatic generation of left ventricle (LV) inner and outer surfaces and valve plane from three- or four-dimensional (respectively static or gated) LV short axis perfusion PET data
• Automatic computation of functional metrics including LV chamber volume and mid-myocardial surface area
• Automatic computation of global quantitative defect size, both in absolute terms and as a percentage of the mid-myocardial surface area
• Automatic generation of segmental perfusion scores (stress, rest, and reversibility)

AutoRecon

AutoRecon offers several automatic processing modules for single-photon emission computed tomography (SPECT) studies. This add-on provides a full-fledged reconstruction program with the following features:

• Automated reconstruction limits selection
• Automated motion correction
• Filtered backprojection and iterative reconstruction
• Automatic reorientation of the transaxial data into short axis images

MoCo (Motion Correction)

MoCo is an application for the automatic and manual correction of SPECT acquisition motion artifacts. Pattern matching and segmentation algorithms are used in conjunction to minimize motion error metrics over the set of acquired projections; the resulting motion corrected projections are then presented to the operator for validation or modification.

Fusion/CT

Fusion/CT module adds features related to coronary CT angiography (CTA) and multi-modality registration.

• 3D display of coronary trees and the 3D LV surfaces with mapped perfusion or viability information
• Automated registration of coronary trees (especially useful for non-hybrid systems)
• Fused image display to assess or correct image registration (for CTA and attenuation CT data)

Companion

Comparison module is a collection of enhancements to QGS, QPS.

• 17-segment scoring (perfusion and function)
• Eccentricity calculation: a measure of ventricular sphericity to assess ventricular remodeling
• Diastolic function: ventricular filling and emptying parameters are extracted from interpolated time-volume curves

PlusPack

PlusPack module groups several useful, advanced quantitative and productivity features to QGS/QPS.

• Motion frozen: compensate for cardiac motion to generate sharper perfusion datasets
• Serial change assessment: directly compare serial studies, bypassing comparisons to statistical databases
• Prone/Supine SPECT perfusion quantification: help eliminate artifacts by merging information from both acquisition positions
• Shape index calculation: quantify ventricular remodeling, an early marker of disease
• Phase analysis: assess mechanical dyssynchrony using powerful quantitative and visual tools

Below are the packages and additional options:

	SPECT Perfusion, Basic	SPECT Perfusion, Deluxe	A La Carte Only
QGS	■	■
QPS	■	■
Companion	■	■
QBS	■	■
PlusPack		■
QPET and Fusion/CT			■
AutoRecon			■
AutoRecon with MoCo (Motion Correction)			■