CR-2 Plus AF

The Canon CR-2 Plus AF Digital Non-Mydriatic Retinal Camera provides Colour and Fundus Autofluorescence (FAF) imaging within a small compact design. FAF imaging offers information on changes of the retina that can’t be made visible with standard colour photography.

The camera enables fast and accurate Auto-Focus, Auto Switching from anterior to retinal observation and Auto Shot. The device also features the unique Photometric Auto-Exposure whereby the flash and observation light intensity is determined automatically during every examination. This is based on real-time measurement of retinal reflectance for perfect images in a single capture, regardless of pupil size or ethnicity.

In addition, the CR-2 Plus AF is equipped with a unique dedicated EOS digital camera for the highest image quality.

See the smallest details, don’t miss pathology

Canon was the very first company to introduce a Non-Mydriatic Retinal Camera as far back as 1976.

Built on this legacy, the CR-2 Plus AF is equipped with superb Canon optics and Canon’s own EOS digital camera technology. This technology includes Canon’s renowned image processing capabilities which have been adapted exclusively for its retinal cameras in order to offer optimal retinal imaging for the highest image quality.

In addition, Canon's unique Opacity Suppression largely suppresses the effects of cataracts and other ocular opacities.

Color

FAF

Ease of use

The CR-2 Plus AF’s compact design results in a short reaching distance and allows the operator to easily keep the patient’s eye open with one hand while offering an excellent view of their eye. The stage part consists of a specially shaped surface to act as grip; it provides easy handling for quick and efficient image capturing.

Centralized controls and multifunctional joystick

The operation panel comes with centralized controls and a multifunctional joystick for intuitive operation. The switches are illuminated for easy operation in darker rooms.

The multifunctional joystick combines many functions:

Controls the up and down movement of the optical head, which is powered for effortless operation.
Apart from the shutter release button, includes an alignment button to switch between the view of the anterior eye and the retina, and a focus ring that can be used for manual focus control.
Switches to FAF mode with the push of a button.

Low flash photography

In addition to the photometric Auto Exposure, the CR-2 Plus AF offers low flash photography. This feature greatly reduces the patients’ discomfort. Workflow is also improved as images of both eyes can be captured without being restricted by the pupils’ size. This is ideal for photophobic patients.

Fixation Lamp shifting presets

The CR-2 Plus AF offers the possibility to pre-set four fixation lamps patterns for internal fixation. Each pattern has a maximum of nine positions. This is an excellent feature when various screening protocols are used.

45 degrees

CR-2 Plus AF provides Non-Mydriatic images at a 45 degrees angle (67.5 degrees when using center of eye ball as reference).

Angle of incidence vs central angle of view

2X Magnification

The CR-2 AF is equipped with a 2X button that provides a 2X digital magnification, such as a 30 degrees image, depending on the setting.

Fundus Autofluorescence (FAF)

Fundus Autofluorescence (FAF) is a diagnostic technique for documenting the deposition of lipofuscin in the retinal pigment epithelium (RPE). As an easy and non invasive technique, it provides information that may otherwise not be clinically detectable. It can be a valuable asset in diagnosing retinal disease.

Since the introduction of fluorescein angiography (FFA) in 1959, ophthalmologists observed that even without the use of fluorescein, parts of the fundus would show areas of faint fluorescence under certain conditions. This naturally occurring fluorescence is mainly caused by Lipofuscin, a fluorescent pigment that accumulates in the RPE as a metabolic byproduct of cell function.

Lipofuscin deposition normally increases with age, but may also occur from RPE cell dysfunction or an abnormal metabolic load on the RPE. FAF imaging can visualize the deposition of lipofuscin in the retinal pigment epithelium (RPE). Areas of excess Lipofuscin accumulation will appear hyperfluorescent. However, when RPE cells die or are absent, LF disappears, leading to hypofluorescence.

Am I missing something without FAF?

In this example, it is clear that the FAF image is showing additional clinical information that can’t be seen in the colour image!

Green Spectrum

The Canon CR-2 Plus AF utilizes green light spectrum to stimulate the retina and capture the emission in the yellow-orange spectrum while utilizing carefully selected matching optical filters. The green spectrum may provide more detail in the fovea, where as blue light tends to be absorbed by the high concentration of macular pigments. An additional advantage of green light is that the longer wavelength tends to have less absorption by the crystalline lens of the eye, especially in patients with cataracts.

CLINICAL FAF images

Normal distribution of lipofuscin

Retinal pigment epithelial atrophy

Karolinska Instutet

“With the extra feature of FAF photography we have discovered retinal changes we have not seen before and which makes us earn more about retinal changes and diseases every day“

Rune Brautaset
Professor
Vice-chairman Committee for Higher Education
Head of division for Eye and Vision
Karolinska Institutet, Stockholm

Wide Field Imaging

With the optional Mosaic software, up to 20 images can be combined into a high-resolution wide field image, including the peripheral retina (up to 85 degrees).

The automatic fixation light guidance of the retinal camera can be of assistance in capturing the images.

Digital Redfree and cobalt image

Without having the requirement to take an additional image, the RX software can create a digital red-free or cobalt image from a colour image. This is based on Canon’s EOS retina technology and its proprietary image processing that uses the digital camera’s original RAW image.

The image quality is fully comparable with those obtained via optical filters.

Digital Redfree

Digital Cobalt

Anterior Segment Photography

The CR-2 Plus AF offers quick and easy anterior segment photography to document the cornea, pupil, eyelid and sclera.

Stereo Photography

The CR-2 AF is suitable for stereo photography by sequentially taking two retinal images to form a stereo pair.

The capture sequence is simple to use with its stereo guides shown on the observation monitor. Alternatively, users can manually create a stereo set as well as a pair in the RX software.

Stereo guide marks

Stereo viewing

A standard commercial optical stereo viewer can be used for reviewing. The individual images of the stereo pair can easily be aligned in the RX software to obtain maximum stereo effect.

Stereo Pair